Artificial Intelligence and Quantitative Pathology

  • Machine learning for cryosection pathology predicts the 2021 WHO classification of glioma.
    MacLean P. Nasrallah*, Junhan Zhao*, Cheng Che Tsai*, David Meredith, Eliana Marostica, Keith L. Ligon, Jeffrey A. Golden, Kun-Hsing Yu.
    Med. 2023 Jun 29. doi: 10.1016/j.medj.2023.06.002. Online ahead of print. [Pubmed] [Codes]
  • Histopathology Images Predicted Multi-Omics Aberrations and Prognoses in Colorectal Cancer Patients.
    Pei-Chen Tsai, Tsung-Hua Lee, Kun-Chi Kuo, Fang-Yi Su, Tsung-Lu Michael Lee, Eliana Marostica, Tomotaka Ugai, Melissa Zhao, Mai Chan Lau, Juha P. Väyrynen, Marios Giannakis, Yasutoshi Takashima, Seyed Mousavi Kahaki, Kana Wu, Mingyang Song, Jeffrey A. Meyerhardt, Andrew T. Chan, Jung-Hsien Chiang, Jonathan Nowak, Shuji Ogino, Kun-Hsing Yu.
    Nature Communications. 2023 Apr 13;14(1):2102. [Pubmed] [Codes]
  • Prediction of early-stage melanoma recurrence using clinical and histopathologic features.
    Guihong Wan*, Nga Nguyen*, Feng Liu*, Mia S. DeSimone, Bonnie W. Leung, Ahmad Rajeh, Michael R. Collier, Min Seok Choi, Munachimso Amadife, Kimberly Tang, Shijia Zhang, Jordan S. Phillipps, Ruple Jairath, Nora A. Alexander, Yining Hua, Meng Jiao, Wenxin Chen, Diane Ho, Stacey Duey, István Balázs Németh, Gyorgy Marko-Varga, Jeovanis Gil Valdés, David Liu, Genevieve M. Boland, Alexander Gusev, Peter K. Sorger, Kun-Hsing Yu^, Yevgeniy R. Semenov^.
    npj Precision Oncology. 2022 Oct 31;6(1):79. [Pubmed]
  • Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcome in Subtypes of Renal Cell Carcinoma.
    Eliana Marostica, Rebecca Barber, Thomas Denize, Isaac S. Kohane, Sabina Signoretti, Jeffrey A Golden, Kun-Hsing Yu.
    Clinical Cancer Research. 2021 May 15;27(10):2868-2878. [Pubmed] [Codes]
  • Integrative Multiomics-histopathology Analysis for Breast Cancer Classification.
    Yasha Ektefaie, William Yuan, Deborah A. Dillon, Nancy U. Lin, Jeffrey A. Golden, Isaac S. Kohane, Kun-Hsing Yu.
    npj Breast Cancer. 2021 Nov 29;7(1):147. [Pubmed] [Codes]
  • Deciphering Serous Ovarian Carcinoma Histopathology and Platinum Response by Convolutional Neural Networks.
    Kun-Hsing Yu, Vincent Hu, Feiran Wang, Ursula Matulonis, George L. Mutter, Jeffrey A. Golden, Isaac S. Kohane.
    BMC Medicine. 2020 Aug 18;18(1):236. [Pubmed] [Codes]
  • Reproducible Machine Learning Methods for Lung Cancer Detection using Computed Tomography Images.
    Kun-Hsing Yu, Tsung-Lu Michael Lee, Ming-Hsuan Yen, S. C. Kou, Bruce Rosen, Jung-Hsien Chiang, Isaac S. Kohane.
    Journal of Medical Internet Research (JMIR). 2020 Aug 5;22(8):e16709. [Pubmed] [Codes]
  • Classifying Non-Small Cell Lung Cancer Types and Transcriptomic Subtypes using Convolutional Neural Networks.
    Kun-Hsing Yu, Feiran Wang, Gerald J. Berry, Christopher Ré, Russ B. Altman, Michael Snyder, Isaac S. Kohane.
    JAMIA. 2020 May 2;27(5):757–769. [PubMed] [Codes]
  • Deep Transfer Learning and Radiomics Feature Prediction of Survival of Patients with High-Grade Gliomas.
    Wei Han, Lei Qin, Camden Bay, Xin Chen, Kun-Hsing Yu, Xiaoyin Xu, Geoffrey Young.
    American Journal of Neuroradiology. 2020 Jan;41(1):40-48. [PubMed]
  • Framing the Challenges of Artificial Intelligence in Medicine.
    Kun-Hsing Yu and Isaac S. Kohane.
    BMJ Quality & Safety. 2019 Mar;28(3):238-241. [PubMed]
  • A Cloud-Based Metabolite and Chemical Prioritization System for the Biology/Disease-Driven Human Proteome Project.
    Kun-Hsing Yu, Tsung-Lu Michael Lee, Yu-Ju Chen, Christopher Ré, Samuel C. Kou, Jung-Hsien Chiang, Michael Snyder, Isaac S. Kohane.
    Journal of Proteome Research. 2018 Dec 7;17(12):4345-4357. [PubMed] [Codes] [Running Server]
  • Systematic Protein Prioritization for Targeted Proteomics Studies through Literature Mining.
    Kun-Hsing Yu, Tsung-Lu Michael Lee, Chi-Shiang Wang, Yu-Ju Chen, Christopher Ré, Samuel C. Kou, Jung-Hsien Chiang, Isaac S. Kohane, Michael Snyder.
    Journal of Proteome Research. 2018 Apr 6;17(4):1383-1396. [PubMed] [Codes] [Running Server]
  • Artificial Intelligence in Healthcare.
    Kun-Hsing Yu, Andrew L. Beam, Isaac S. Kohane.
    Nature Biomedical Engineering. 2018 Oct;2(10):719-731. [PubMed]
  • Association of Omics Features with Histopathology Patterns in Lung Adenocarcinoma.
    Kun-Hsing Yu, Gerald J. Berry, Daniel L. Rubin, Christopher Ré, Russ B. Altman, Michael Snyder.
    Cell Systems. 2017 Dec 27;5(6):620-627.e3. [PubMed]
  • Predicting Non-Small Cell Lung Cancer Prognosis by Fully Automated Microscopic Pathology Image Features.
    Kun-Hsing Yu, Ce Zhang, Gerald J. Berry, Russ B. Altman, Christopher Ré, Daniel L. Rubin, Michael Snyder.
    Nature Communications. 2016 Aug 16;7:12474. [PubMed] [Source Codes] [Dataset of Image Features]
  • Deep Decision Support for Lymph Node Metastatic Risk Evaluation.
    Eliana Marostica, Kun-Hsing Yu.
    EBioMedicine. 2020 Nov 4;62:103105. [PubMed]
  • Quantitative Pathology Analysis and Diagnosis using Neural Networks.
    Kun-Hsing Yu.
    U.S. Patent 10,832,406. Patent assigned to Harvard University.

Integrative Multi-Omics Analyses

  • Omics AnalySIs System for PRecision Oncology (OASISPRO): A Web-Based Omics Analysis Tool for Clinical Phenotype Prediction.
    Kun-Hsing Yu, Michael R. Fitzpatrick, Luke Pappas, Warren Chan, Jessica Kung, Michael Snyder.
    Bioinformatics. 2018 Jan 15;34(2):319-320. [PubMed] [Codes] [Running Server]
  • Predicting Ovarian Cancer Patients' Clinical Response to Platinum-based Chemotherapy by their Tumor Proteomic Signatures.
    Kun-Hsing Yu, Douglas A. Levine, Hui Zhang, Daniel W. Chan, Zhen Zhang, Michael Snyder.
    Journal of Proteome Research. 2016 Aug 5;15(8):2455-65. [PubMed]
  • Omics Profiling in Precision Oncology.
    Kun-Hsing Yu, Michael Snyder.
    Molecular & Cellular Proteomics. 2016 Aug;15(8):2525-36. [PubMed]
  • Deep Proteogenomic Characterization of Human Ovarian Cancer.
    Hui Zhang, Tao Liu, Zhen Zhang, Samuel H Payne, Jason E McDermott, Jian-Ying Zhou, Vladislav A Petyuk, Lily Chen, Debjit Ray, Shisheng Sun, Feng Yang, Bai Zhang, Jing Wang, Seong Won Cha, Lijun Chen, Sunghee Woo, Punit Shah, Paul Aiyetan, Yuan Tian, Caitlin Choi, Marina A Gritsenko, Ronald J Moore, Matthew E Monroe, Kun-Hsing Yu, David Tabb, David Fenyo, Vineet Bafna, Joseph Wang, Ie-Ming Shih, Akhilesh Pandey, Bing Zhang, Michael Snyder, Doug Levine, Richard D Smith, Daniel W Chan, Karin D Rodland and the TCGA investigators.
    Cell. 2016 Jul 28;166(3):755-65. [PubMed]
  • The Genetic Predisposition to Bronchopulmonary Dysplasia.
    Kun-Hsing Yu*, Jingjing Li*, Michael Snyder, Gary M. Shaw, Hugh M. O'Brodovich.
    Current Opinion in Pediatrics. 2016 Jun;28(3): 318-23. [PubMed]
  • Transcriptomic Analysis of Inter and Intra Patient Variation in hiPSC-Cardiomyocytes is Predictive of Patient-Specific Cardiotoxicity.
    Elena Matsa, Paul W. Burridge, Kun-Hsing Yu, John H. Ahrens, Haodi Wu, Praveen Shukla, Jared M. Churko, Joseph D. Gold, Michael P. Snyder, Joseph C. Wu.
    Cell Stem Cell. 2016 Sep 1;19(3):311-25. [PubMed]
  • Exome Sequencing of Neonatal Blood Spots Identifies Genes Implicated in Bronchopulmonary Dysplasia.
    Jingjing Li*, Kun-Hsing Yu*, John Oehlert, Laura L Jeliffe-Pawlowski, Jeffrey B Gould, David K Stevenson, Michael Snyder, Gary M Shaw, Hugh M O’Brodovich.
    American Journal of Respiratory and Critical Care Medicine. 2015 Sep 1;192(5):589-96. [PubMed]
  • Prioritization of Cancer Marker Candidates Based on the Immunohistochemistry Staining Images Deposited in the Human Protein Atlas.
    Su-Chien Chiang, Chia-Li Han, Kun-Hsing Yu, Yu-Ju Chen, Kun-Pin Wu.
    PLoS One. 2013 8(11): e81079. [PubMed]
  • An Informatics-Assisted Label-free Approach for Personalized Tissue Membrane Proteomics: Case Study on Colorectal Cancer.
    Chia-Li Han, Jinn-Shiun Chen, Err-Cheng Chan, Chien-Peng Wu, Kun-Hsing Yu, Chia-Feng Tsai, Guei-Tian Chen, Chih-Wei Chien, Yung-Bin Kuo, Pei-Yi Lin, Chung-Chuan Chan, Jao-Song Yu, Yu-Ju Chen.
    Molecular & Cellular Proteomics. 2011 Apr;10(4):M110.003087. [PubMed]
  • Evaluation of Taroni et al.: Understanding Rare Diseases by MultiPLIER.
    Kun-Hsing Yu.
    Cell Systems. 2019 May 22;8(5):359-360. [PubMed]

Big Data in Medicine

  • Influence of melanoma type on incidence and downstream implications of cutaneous immune-related adverse events in the setting of immune checkpoint inhibitor therapy.
    Nga Nguyen, Guihong Wan, Pearl Ugwu-Dike, Nora A. Alexander, Neel Raval, Shijia Zhang, Ruple Jairath, Jordan Phillipps, Bonnie Leung, Katie Roster, Jayhyun Seo, Chenyue Lu, Kimberly Tang, Min Seok Choi, Mia S. DeSimone, Nicholas Theodosakis, Munachimso Amadife, Nevada Cox, Thomas K. Le, Feng Liu, Wenxin Chen, Xue Bai, Genevieve Boland, David Liu, Marc S. Hurlbert, Nicole LeBoeuf, Kerry L. Reynolds, Kun-Hsing Yu, Hensin Tsao, Maryam Asgari, Alexander Gusev, Shawn G. Kwatra, Yevgeniy R. Semenov.
    Journal of the American Academy of Dermatology. 2023 Feb 22;S0190-9622(23)00204-9. [Pubmed]
  • Cutaneous immune-related adverse events are associated with longer overall survival in advanced cancer patients on immune checkpoint inhibitors: a multi-institutional cohort study.
    Shijia Zhang, Kimberly Tang, Guihong Wan, Nga Nguyen, Chenyue Lu, Pearl Ugwu-Dike, Neel Raval, Jayhyun Seo, Nora A. Alexander, Ruple Jairath, Jordan Phillipps, Bonnie W. Leung, Kathleen Roster, Wenxin Chen, Leyre Zubiri, Genevieve Boland, Steven T. Chen, Hensin Tsao, Shadmehr Demehri, Nicole R. LeBoeuf, Kerry L. Reynolds, Kun-Hsing Yu, Alexander Gusev, Shawn G. Kwatra, Yevgeniy R. Semenov.
    Journal of the American Academy of Dermatology. 2023 Jan 31;S0190-9622(23)00153-6. [Pubmed]
  • Large-Scale Real-World Data Analysis Identifies Comorbidity Patterns in Schizophrenia.
    Chenyue Lu, Di Jin, Nathan Palmer, Kathe Fox, Isaac S. Kohane, Jordan W. Smoller, Kun-Hsing Yu.
    Translational Psychiatry. 2022 Apr 11;12(1):154. doi: 10.1038/s41398-022-01916-y.[PubMed]
  • The impact of stage-related features in melanoma recurrence prediction: A machine learning approach.
    Guihong Wan, Bonnie Leung, Nga Nguyen, Mia S. DeSimone, Feng Liu, Min Seok Choi, Diane Ho, Valerie Laucks, Stacey Duey, Ryan J. Sullivan, Genevieve M. Boland, Nicole R. LeBoeuf, David Liu, Alexander Gusev, Shawn G. Kwatra, Peter K. Sorger, Kun-Hsing Yu, Yevgeniy R. Semenov.
    JAAD International. 2022 Aug 30;10:28-30.[PubMed]
  • Outdoor Mass Gathering Events and SARS-CoV-2 Infection in Catalonia (North-East Spain).
    Oren Miron, Kun-Hsing Yu.
    Lancet Regional Health Europe. 2022 Mar 22;15:100350. doi: 10.1016/j.lanepe.2022.100350.[PubMed]
  • Survival Prediction After Neurosurgical Resection of Brain Metastases: A Machine Learning Approach.
    Alexander F.C. Hulsbergen, Yu Tung Lo, Ilia Awakimjan, Vasileios K. Kavouridis, John G. Phillips, Timothy R. Smith, Joost J.C. Verhoeff, Kun-Hsing Yu, Marike L.D. Broekman, Omar Arnaout.
    Neurosurgery. 2022 Sep 1;91(3):381-388. [Pubmed]
  • Prognostic role of inflammatory diets in colorectal cancer overall and in strata of tumor-infiltrating lymphocyte levels.
    Tomotaka Ugai, Li Liu, Fred K. Tabung, Tsuyoshi Hamada, Benjamin W. Langworthy, Naohiko Akimoto, Koichiro Haruki, Yasutoshi Takashima, Kazuo Okadome, Hidetaka Kawamura, Melissa Zhao, Seyed Mostafa Mousavi Kahaki, Jonathan N. Glickman, Jochen K. Lennerz, Xuehong Zhang, Andrew T. Chan, Charles S. Fuchs, Mingyang Song, Molin Wang, Kun-Hsing Yu, Marios Giannakis, Jonathan A. Nowak, Jeffrey A. Meyerhardt, Kana Wu, Shuji Ogino, Edward L. Giovannucci.
    Clinical Translational Medicine. 2022 Nov;12(11):e1114. [Pubmed]
  • Association of Race and Socioeconomic Disadvantage With Missed Telemedicine Visits for Pediatric Patients During the COVID-19 Pandemic.
    Evan Brociner, Kun-Hsing Yu, Isaac S. Kohane, McGreggor Crowley.
    JAMA Pediatrics. 2022 May 23:e221510. doi: 10.1001/jamapediatrics.2022.1510.[PubMed]
  • Ten Quick Tips for Deep Learning in Biology.
    Benjamin D. Lee, Anthony Gitter, Casey S. Greene, Sebastian Raschka, Finlay Maguire, Alexander J. Titus, Michael D. Kessler, Alexandra J. Lee, Marc G. Chevrette, Paul Allen Stewart, Thiago Britto-Borges, Evan M. Cofer, Kun-Hsing Yu, Juan Jose Carmona, Elana J. Fertig, Alexandr A. Kalinin, Brandon Signal, Benjamin J. Lengerich, Timothy J. Triche Jr., Simina M. Boca.
    PLoS Computational Biology. 2022 Mar 24;18(3):e1009803.[PubMed]
  • An Observational Study on the Molecular Profiling of Primary Melanomas Reveals a Progression Dependence on Mitochondrial Activation.
    Jeovanis Gil, Melinda Rezeli, Elmar G. Lutz, Yonghyo Kim, Yutaka Sugihara, Johan Malm, Yevgeniy R. Semenov, Kun-Hsing Yu, Nga Nguyen, Guihong Wan, Lajos V. Kemény, Sarolta Kárpáti, István Balázs Németh, György Marko-Varga.
    Cancers. 2021 Dec 1;13(23):6066.[PubMed]
  • Real-World Data Analyses Unveiled the Immune-Related Adverse Effects of Immune Checkpoint Inhibitors Across Cancer Types.
    Feicheng Wang, Shihao Yang, Nathan Palmer, Kathe Fox, Isaac S. Kohane, Katherine P. Liao, Kun-Hsing Yu*, S. C. Kou*.
    npj Precision Oncology. 2021 Sep 10;5(1):82. doi: 10.1038/s41698-021-00223-x. [PubMed]
  • Epidemiology and Risk Factors for the Development of Cutaneous Toxicities in Patients Treated with Immune-Checkpoint Inhibitors: A United States Population-Level Analysis.
    Shannon Wongvibulsin, Vartan Pahalyants, Mark Kalinich, William Murphy, Kun-Hsing Yu, Feicheng Wang, Steven T Chen, Kerry Reynolds, Shawn G Kwatra, Yevgeniy R Semenov.
    Journal of the American Academy of Dermatology. 2021 Apr 2;S0190-9622(21)00661-7. doi: 10.1016/j.jaad.2021.03.094. [PubMed]
  • Prediction of Severe Immune-Related Adverse Events Requiring Hospital Admission in Patients on Immune Checkpoint Inhibitors: Study of a Population Level Insurance Claims Database from the USA.
    Mark Kalinich, William Murphy, Shannon Wongvibulsin, Vartan Pahalyants, Kun-Hsing Yu, Chenyue Lu, Feicheng Wang, Leyre Zubiri, Vivek Naranbhai, Alexander Gusev, Shawn G Kwatra, Kerry L Reynolds, Yevgeniy R Semenov.
    Journal for Immunotherapy of Cancer. 2021 Mar;9(3):e001935. [PubMed]
  • Temporal Bias in Case-Control Design: Preventing Reliable Predictions of the Future.
    William Yuan, Brett K Beaulieu-Jones, Kun-Hsing Yu, Scott L Lipnick, Nathan Palmer, Joseph Loscalzo, Tianxi Cai, Isaac S Kohane.
    Nature Communications. 2021 Feb 17;12(1):1107. [PubMed]
  • Classification of Glioblastoma versus Primary Central Nervous System Lymphoma using Convolutional Neural Networks.
    Malia McAvoy, Paola Calvachi Prieto, Jakub R Kaczmarzyk, Iván Sánchez Fernández, Jack McNulty, Timothy Smith, Kun-Hsing Yu, William B. Gormley, Omar Arnaout.
    Scientific Reports. 2021 Jul 26;11(1):15219. doi: 10.1038/s41598-021-94733-0. [PubMed]
  • The Phenotypical Implications of Immune Dysregulation in Fragile X Syndrome.
    Kun-Hsing Yu, Nathan Palmer, Kathe Fox, Lisa Prock, Kenneth D. Mandl, Isaac S. Kohane, Daria Prilutsky.
    European Journal of Neurology. 2020 Mar;27(3):590-593. [PubMed]
  • Examining the Use of Real-World Evidence in the Regulatory Process.
    Brett K. Beaulieu-Jones, Samuel G. Finlayson, William Yuan, Russ B. Altman, Isaac S. Kohane, Vinay Prasad, Kun-Hsing Yu.
    Clinical Pharmacology & Therapeutics. 2020 Apr;107(4):843-852. [PubMed]
  • COVID-19 Infections Following Physical School Reopening.
    Oren Miron, Kun-Hsing Yu, Rachel Wilf-Miron, Isaac Kohane, Nadav Davidovitch.
    Archives of Disease in Childhood. 2020 Dec 7;archdischild-2020-321018. [PubMed]
  • Prolonged Auditory Brainstem Response in Universal Hearing Screening of Newborns with Autism Spectrum Disorder.
    Oren Miron, Rafael E. Delgado, Christine F. Delgado, Elizabeth A. Simpson, Kun-Hsing Yu, Anibal Gutierrez, Guangyu Zeng, Jillian N Gerstenberger, Isaac S Kohane.
    Autism Research. 2020 Nov 2. doi: 10.1002/aur.2422. [PubMed]
  • Autoimmune Effects of Lung Cancer Immunotherapy Revealed by Data-Driven Analysis on a Nationwide Cohort.
    Shihao Yang*, Kun-Hsing Yu*, Nathan Palmer, Kathe Fox, S. C. Kou, Isaac S. Kohane.
    Clinical Pharmacology & Therapeutics. 2020 Feb;107(2):388-396. [PubMed]
  • Evaluation of the Association of Bariatric Surgery with Subsequent Depression.
    William Yuan, Kun-Hsing Yu, Nathan Palmer, Fatima Cody Stanford, Isaac Kohane.
    International Journal of Obesity. 2019 Dec;43(12):2528-2535. [PubMed]
  • Suicide Rates Among Adolescents and Young Adults in the United States, 2000-2017.
    Oren Miron, Kun-Hsing Yu, Rachel Wilf-Miron, Isaac S. Kohane.
    JAMA. 2019 Jun 18;321(23):2362-2364. [PubMed]
  • Deep Learning in Rare Disease. Detection of Tubers in Tuberous Sclerosis Complex.
    Iván Sánchez Fernández, Edward Yang, Paola Calvachi, Marta Amengual-Gual, Joyce Y. Wu, Darcy Krueger, Hope Northrup, Martina E. Bebin, Mustafa Sahin, Kun-Hsing Yu, Jurriaan M. Peters, on behalf of the TACERN Study Group.
    PLoS One. 2020 Apr 29;15(4):e0232376. [PubMed]
  • Proceedings of the Fourth International Molecular Pathological Epidemiology (MPE) Meeting.
    Peter T. Campbell, Christine B. Ambrosone, Reiko Nishihara, Hugo J. W. L. Aerts, Melissa Bondy, Nilanjan Chatterjee, Montserrat Garcia-Closas, Marios Giannakis, Jeffrey A. Golden, Yujing J. Heng, N. Sertac Kip, Jill Koshiol, X. Shirley Liu, Camila M. Lopes-Ramos, Lorelei A. Mucci, Jonathan A. Nowak, Amanda I. Phipps, John Quackenbush, Robert E. Schoen, Lynette M. Sholl, Rulla M. Tamimi, Molin Wang, Matty P. Weijenberg, Catherine J. Wu, Kana Wu, Song Yao, Kun-Hsing Yu, Xuehong Zhang, Timothy R. Rebbeck, Shuji Ogino.
    Cancer Causes & Control. 2019 Aug;30(8):799-811. [PubMed]
  • Data-Driven Analyses Revealed the Comorbidity Landscape of Tuberous Sclerosis Complex.
    Kun-Hsing Yu, Oren Miron, Nathan Palmer, Dario Lemos, Kathe Fox, S. C. Kou, Mustafa Sahin, Isaac S. Kohane.
    Neurology. 2018 Nov 20;91(21):974-976. [PubMed]
  • Biomedical Informatics Advancing the National Health Agenda: The AMIA 2015 Year-in-Review in Clinical & Consumer Informatics.
    Kirk Roberts, Mary Regina Boland, Lisiane Pruinelli, Jina Dcruz, Andrew Berry, Mattias Georgsson, Rebecca Hazen, Raymond F. Sarmiento, Uba Backonja, Kun-Hsing Yu, Yun Jiang, Patricia Flatley Brennan.
    Journal of American Medical Informatics Association. 2017 Apr 1;24(e1):e185-e190. [PubMed]
  • Artificial Intelligence in Research.
    Mrinal Musib, Feng Wang, Michael A Tarselli, Rachel Yoho, Kun-Hsing Yu, Rigoberto Medina Andrés, Noah F. Greenwald, Xubin Pan, Chien-Hsiu Lee, Jian Zhang, Ken Dutton-Regester, Jake Wyatt Johnston, Icell Mahmoud Sharafeldin.
    Science. 2017 Jul 7;357(6346):28-30.[PubMed]
  • Harnessing Big Data for Precision Medicine: Infrastructures and Applications.
    Kun-Hsing Yu, Steven Hart, Rachel Goldfeder, Qiangfeng Cliff Zhang, Stephen Parker, Michael Snyder.
    Pacific Symposium on Biocomputing. 2017;22:635-639. [PubMed]
  • A Tale of Two Cities: Understanding Constructs of Medical Professionalism in Two Chinese Cultural Contexts.
    Ming-Jung Ho, Kun-Hsing Yu, Hui Pan, Jessie L. Norris, You-Sin Liang, Jia-Ning Li, David Hirsh.
    Academic Medicine. 2014 Jun;89(6):944-50. [PubMed]
  • Does One Size Fit All? – Building a Framework for Medical Professionalism.
    Ming-Jung Ho, Kun-Hsing Yu, David Hirsh, Tien-Shiang Huang, Pan-Chyr Yang.
    Academic Medicine. 2011 Nov;86(11):1407-1414. [PubMed]